An unstoppable Brackley side will hope to do the double over their fellow National League North competitors, in York City, where three points would also keep The Saints in top spot, ahead of Gateshead.
In Brackley's last outing, they were held to a stalemate by bogey team Curzon Ashton, despite being thwarted twice by the woodwork. However, it's not unusual to witness a Saints match with few goals, with Brackley being the lowest scorers in the top ten, coincidentally sharing the record with York.
On the topic of York City, they will come into this game off the back of a second consecutive loss and this upcoming away match will be the second of four in a row for the demoralised Minstermen.
Last Saturday, City couldn't produce another upset as they were kicked out of the FA Trophy by Bromley, before being put to the sword against Kettering, on a horrible night which ended in a 2-0 defeat.
It's coming to the business end of the season now and Brackley can't afford to pick up any injuries. Only two players are affected by injury at the moment, with them being Brad Rolt and Tre Mitford, although there is a slight chance of the duo making it into the matchday 16.
After changing shape completely on Tuesday night and failing, John Askey will be hoping he can revert back to a 4-3-3, given right-back Michael Duckworth returns from a groin injury picked up during the week. If so, loan defender Sam Sanders may lose his place in the starting lineup.
Another hopeful to come back into the squad is Mitch Hancox, who was ruled out in midweek due to illness, and could be back for the big game on Saturday.
Brackley Town: Lewis; Myles, Dean, Lomas; Franklin, Walker, Armson, Lowe, Murombedzi; Ndlovu, York
York City: Jameson; Duckworth, Kouogun, Brown, Barrow; Wright, McLaughlin, Dyson; Willoughby, Kouhyar, Donaldson
Ones to watch
Ndlovu has been banging in goals left, right and centre for Brackley over the last few years, and the prolific striker has recorded 13 goals and counting so far this league campaign, ranking him 6th in the top scorers.
Towards the back end of March, Ndlovu achieved the feat of scoring all The Saints' goals in three consecutive matches and will be hoping to net against York for his first goal in April.
After signing from Hereford last month, York City fans will get to see Maziar Kouhyar for the second time, after featuring in City's unfortunate defeat on Tuesday.
Deemed "the best player in the league," the Afghan midfielder has already scored five times for Hereford in 30 appearances this campaign. Manager John Askey will be hoping his newest recruit can help fire The Minstermen back into winning form with an impact against the league leaders.
For The Minstermen, they also had a 100% record... but the complete opposite of what their opponents had.
The visitors began the brightest, but it was York that took the lead, as Akil Wright headed home from a corner 22 minutes in.
It looked like that goal was going to be the winner for City, but The Saints found themselves back level with five minutes to go - threat Matt Lowe was lucky as his cross-shot found the back of the net.
The hosts were soon made to pay for sitting back and defending a lead, as that lead vanished completely when Brackley took all three points in the 88th minute, courtesy of Lee Ndlovu, who slotted it past Pete Jameson to send his side back to Northamptonshire, 2-1 winners.
How to watch and listen
Tickets and admission are available for the following prices HERE:
Under 18: £5
Junior U10's: £1
Other than watching the game live at St James' Park, there will be no livestream, but commentary is available from BBC Radio York.
Kickoff is at 15:00 GMT.
Both clubs will be providing live updates through their social media channels.