Burnley welcome in-form Liverpool to Turf Moor in a crucial fixture in the battle for Champions League football.
Sean Dyche’s men will be looking to bounce back from a disastrous 4-0 defeat against Leeds United in their last outing.
Meanwhile, the Reds have won their last three matches following Alisson’s remarkable injury-time winner at West Brom at the weekend.
Jurgen Klopp's side are just a point behind fourth-placed Chelsea with two games to go, and the race for a top four spot looks set to go down to the wire.
England goalkeeper Nick Pope is “touch and go” after missing Saturday’s loss to Leeds through injury.
Phil Bardsley and Dale Stephens have both had operations, while Robbie Brady and Kevin Long remain sidelined.
As for the visitors, Naby Keita and Diogo Jota both miss out but Alex Oxlade-Chamberlain is back from illness.
Burnley: Peacock-Farrell, Lowton, Tarkowski, Mee, Taylor, Brownhill, Westwood, Cork, McNeil, Vydra, Wood
Liverpool: Alisson, Alexander-Arnold, Williams, Phillips, Robertson, Thiago, Fabinho, Wijnaldum, Salah, Firmino, Mane
Burnley could do the league double over Liverpool for the first time since 1929-30
However, Dyche’s men have lost five of their last six Premier League home games against the Reds
- Liverpool have won just three of their 11 league matches against the bottom six this season
The Clarets ended Liverpool's 68-game unbeaten home run in the Premier League when the sides met at Anfield back in January.
Ashley Barnes got the only goal from the penalty spot after a resilient defensive display from Dyche's men.
The hosts’ best chance fell to Divock Origi, who was denied by the woodwork after pouncing on Ben Mee's slip.
The win was Burnley's first at Anfield since 1974.
How to watch
Wednesday’s game is live on Sky Sports Premier League for UK viewers (KO 8:15pm).