Pep Guardiola's side enter the season as bookmakers favourites as they aim to defend their Premier League crown, having won the competition in three of the last four seasons.
The star-studded squad in East Manchester won't be settling for just the one trophy this season though, with the League Cup, FA Cup and the long awaited UEFA Champions League well within their sights.
It's 10 trophies and counting for Guardiola during his City stint so far, but will he be adding to his glittering resume this season?
It's been a rollercoaster transfer window for Manchester City so far, yet they have only made three official signings thus far.
Veteran stopper Scott Carson made his loan move permanent as he put pen to paper on a one-year deal back in January, whilst there was the small matter of the £100,000,000 deal to bring Jack Grealish to East Manchester.
Brazilian youngster Kayky has also made his move to Manchester City official, with the 18-year-old signing a long term deal for a fee in the region of £9,000,000.
There have been some notable outgoing too, with Angeliño completing a move to RB Leipzig following a successful loan spell last season. Jack Harrison has made his move to Leeds United permanent after two years on loan at Elland Road, whilst Lukas Nmecha has joined Bundesliga outfit VfL Wolfsburg.
A certain English striker has also been linked with a move to the Etihad, but more on that a little bit later...
Where The Season Can Be Won And Lost
Squad rotation will once again be key to Manchester City's success this season, with the strength in depth key to their battle on all four fronts. The Citizens can expect to be playing three fixtures a week from November onwards, so keeping those legs fresh will be vital.
The arrival (or lack of) of Harry Kane could also be key to the sides success, particularly on a European front. The Englishman has made no secret of his desire to force through a switch to Manchester City, although whether or not it will be given the green light remains to be seen.
The 28-year-old is one of few strikers in world football that could fill the void left by Sergio Aguero, and with Gabriel Jesus' long-term future at the club under scrutiny, it seems imperative that the Citizens go out and pick up a striker of Kane's calibre.
One to Watch
The 21-year-old was in and out of the side last season following his £21,000,000 move from Valencia, with 12 months of Guardiola tutelage under his belt, we are expecting the youngster to light up this Manchester City side as soon as Pep lets the shackles off.
If City can't force through a move for Kane, then Pep may have to look to his academy for a back up to Jesus. And luckily for Manchester City's gaffer, he has one of the most prolific youngsters in world football to call upon.
The PL2 POTS has been likened to Kane due to his physical presence and eye for goal, and should City opt against sending him out on loan, he should be given the chance to prove his worth amongst the senior members of the squad.
What To Expect
Expect a long old season yet again, as the Citizens fight for as many trophies as they can hold. There is no doubt that last seasons UCL final heartbreak will have the squad craving revenge in Europe, although PSG may have something to say about that!
The impressive transfer business of the likes of Chelsea and Manchester United mean that it is unlikely we will see any side cruise their way to the title as we saw from City and Liverpool in the two previous, so expect to see many nervy games as we approach the latter months of the season.
The arrival of Kane would take this squad to a whole new stratosphere, but with a plethora of stars at Guardiola's disposal already, we can't see a scenario in which they aren't competing for the crown come May.
Predicted finish: 1st.