The Moors fell to a 2-0 defeat on Tuesday against Bradford (Park Avenue) after getting reduced to ten men following a red card for James Curtis.
After his red card on Tuesday, James Curtis will be available for selection as it takes the National League seven days to process red cards.
Jamie Chandler and Jordan Preston missed Tuesday's game against Park Avenue with injuries and were replaced by Ethan Brierley and Luke Spokes.
The word injury is all too familiar at Leamington at the moment with several key players out. It was announced last week that striker Kelsey Mooney had done his ACL in the Brakes' away fixture at Farsley Celtic leaving the former Aston Villa and Scunthorpe man sidelined for the foreseeable future as the club sorts his operation.
Top goalscorer Dan Turner has also been out injured but Paul Holleran was hopeful he will be able to take part in County Durham. Left back Steph Morley played through an injury in the Darlington defeat which made him miss the fixture at York City the weekend before.
Spennymoor Town: Flatters, Richardson, Curtis, Tait, Pye, Ramshaw, Brierley, Spokes, Oyibo, Thewlis, Taylor
Leamington: Hawkins, Meredith, Morley, Clarke, Mace, Lane, Williams, Walker, Turner, Edwards, Kelly-Evans
Ones to watch
Taylor will be looking to get revenge against Leamington, he saw his penalty saved by Jake Weaver in the return fixture which meant the Moors went home empty handed.
Dan Meredith has been a bright spark for Leamington this season, and he came closest to scoring for the Warwickshire side last Saturday with a thunderous effort from 30 yards which hit the bar.
The Scottish youth international and former West Brom u23 player who has also spent time at Maidstone United has been tipped to be the next Brakes player to go into the full time game with a string of Man of the Match performances this season from right back.
Two quick fire second half goals from Leamington shocked Spennymoor and sent shockwaves across the National League North. Dan Turner poached first before captain Jack Edwards headed in to hear the Harbury Lane roar that had not been heard in over a year.
Rob Ramshaw's late goal meant nothing with Glen Taylor seeing his penalty saved by Jake Weaver to earn Leamington an impressive three points.
What the managers have said
Joint manager Bernard Morley showed a bit of worry in his post match chat with Spennymoor's YouTube channel, noting that "we've failed to score again at home which of course is a concern for us. We've got to dust ourselves down, get into training on Thursday night, work hard, and look at it again on Saturday."
The longest serving manager in the league Paul Holleran spoke to Leamington FCTV after their loss to Darlo and looked into the struggles for sides with smaller squads such as Leamington, explaining that "the registration deadline going (this early) is unusual. The deadline goes and there's still ten games to go and for small clubs it's tough. It's alright for sides with their big squads but it stretches the part time clubs but we've got to deal with it."
He voiced the fans' frustration at the lack of goals saying "we have all been a bit frustrated the last couple of weeks, we all want to see more goals but there's one thing you can't knock is how hard everyone's working and we'll continue to do that."
How to watch
There is no television coverage of this fixture with it falling at 3pm on Saturday but you can catch the game on both clubs' social media channels as well as live commentary on DurhamOnAir.
Kick off at The Brewery Field is 15:00 BST.