Manchester United and Liverpool face off in the Premier League in the re-arranged fixture after the initial game was postponed due to protests that were going on at and inside Old Trafford earlier this month.
United - who sit second - pretty much have Champions League qualification in the bag, they're 12 points clear of The Hammers who are in fifth place.
Ole Gunnar Solskjær fielded a different team to what United fans are used to in Tuesday nights defeat to Leicester City. Youngsters Amad Diallo, Anthony Elanga and goal scorer on the day, Mason Greenwood, all started that game.
It is expected that Solskjær will freshen up his side against Liverpool and will welcome back those who were given a rest on Tuesday night. Tuesdays game saw the United manager make 10 changes, only keeping the regular starter and in-form Greenwood in the side.
The young attacker may only make the bench on Thursday night but could feature later on in the game. Unfortunately for The Red Devils Harry Maguire remains unavailable and it is looking likely that he could miss United's remaining Premier League games.
As for Liverpool, centre backs Virgil Van Dijk, Joel Matip and Joe Gomez all remain on the side lines for Jurgen Klopp's men. Fellow defenders Ben Davies and Ozan Kabak are also unavailable.
James Milner and Jordan Henderson will also be missing for Liverpool. Divock Origi and Naby Keita both have knocks.
Manchester United: Henderson; Wan-Bissaka, Lindelof, Bailly, Shaw; Fred, McTominay; Rashford, Fernandes, Pogba; Cavani
Liverpool: Alisson; Alexander-Arnold, Phillips, Williams, Robertson; Fabinho, Wijnaldum, Thiago; Mane, Jota, Salah
Ones to watch
Manchester United - Edinson Cavani
Cavani is in some fine form at the moment and to United fans delight, the 34-year-old signed a one year extension this week to stay at the Theatre of Dreams. United fans can't wait to get into Old Trafford to see El Matador live and in the flesh.
He has scored eight goals in his last eight appearances in all competitions for United. Four of those games have been when Cavani has come off of the bench.
In the Premier League, the veteran striker has scored nine goals in total, six of those have been headers. With Liverpool's defensive injuries, they could really struggled to control United's number seven.
Liverpool - Mohamed Salah
Salah is Liverpool's top scorer this season. With 20 league goals to his name the Egyptian is second in the race for the Premier League Golden Boot, one goal behind Harry Kane.
This is now the third season, out of four, that Salah has managed to hit the 20 goal mark in the league. The 28-year-old also scored both the goals against United in his sides 3-2 defeat to The Reds in the FA Cup earlier on this season.
How to watch and kick off time
The game will kick off on Thursday evening (13/05/2021) at 20:15 BST. It will be broadcasted live on Sky Sports Main Event and Sky Sports Premier League.