The home side will look to maintain their assault on automatic promotion when they take on Yorkshire Rivals Rotherham United tomorrow evening.
Following a fantastic 5-2 victory against Burnley last time out, Heckingbottom's men are hoping to go level on points with the Clarets.
For the newly promoted visitors, they are without a win in their last five league matches, so will be searching for an upset.
Rotherham find themselves in 17th position in the league table and will be aiming to stride further away from the relegation zone with a win at Bramall Lane.
The Millers are on a run of three straight defeats under Matthew Taylor, which have all been decided by a single goal which will come as a major frustration to the manager.
In their last outing, Rotherham were on the end of a narrow 2-1 loss to Norwich, as a goal from Oliver Rathbone was cancelled out by efforts from Kenny McLean and Aaron Ramsey.
The last time the two Yorkshire sides met was in March 2019 where Sheffield United were victorious with a 2-0 home win.
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Team News
Sheffield United will be without stars, Daniel Jebbison and Sander Berge this Tuesday night due to ligament injuries.
The Blades will also have to contend without Jayden Bogle, Rhian Brewster, Tommy Doyle, Rhys Norrington-Davies, Max Lowe and Jack O'Connell for the clash owing to various concerns.
Alternatively, Rotherham are injury free going into the game, however Wes Harding and Ben Wiles could pick up a one match suspension if they are to be booked.
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Likely Lineups
Sheffield United (5-3-2)
Foderingham; Basham, Egan, Ahmedhodzic; Baldock, Doyle, Norwood, Osborn; Sharp, Ndiaye; McBurnie
Rotherham (3-5-1-1)
Johansson; Harding, Wood, Peltier; Brammall, Wiles, Barlaser, Rathbone, Norton-Cuffy; Washington, Ogbene
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Key Players
With a man of the match performance in two out of the last three games to help his team to victory, the 22-year-old will be looking to grab a goal for the fourth consecutive game in a row.
After tallying six assists this campaign already, joint first with four others, the Englishman has been Rotherham's danger man this season, and will be their main threat on the night.
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Match Details
Where is the game being played?
The game will be played at Sheffield United's home ground, Bramall Lane, in Sheffield, United Kingdom.
What time is kick off?
Kick-off is at 19:45 (BST) on Tuesday, November 8.
How can I watch?
The game will be on Sky Sports Football through the Red Button on Tuesday evening. Sky Q customers can watch matches on the Red Button in HD at no extra cost. Coverage will begin at 7.40pm, five minutes before kick off.