Nottingham Forest look to cause another shock as the Reds head to London to face Arsenal at the Emirates Stadium.
The Reds picked up just their second win since returning to the Premier League with a 1-0 victory over Liverpool thanks to a goal by Taiwo Awoniyi and a victory here sees them off the foot of the table.
A defeat to PSV Eindhoven in the UEFA Champions League group stages was the Gunners' first defeat in all competitions since early September, but a win here would see them leapfrog Manchester City and go top of the table.
These two sides met in the third round of last season's FA Cup with Forest coming out on top 1-0 on a goal by Lewis Grabban.
Team news
The Gunners will assess the fitness of Oleksandr Zinchenko as the full-back continues to battle a calf injury.
Matt Turner remains out with a groin injury and Emile Smith-Rowe (groin) and Mohamed Elneny (hamstring) join him on the sidelines.
Gabriel Magalhaes limped off in the Europa League defeat to PSV Eindhoven and is a doubt to feature here.
Lewis O'Brien is in contention to return after returning to training following an illness.
The Reds picked up no new injury concerns in the shock win over Liverpool.
Moussa Niakhate (hamstring) and Omar Richards (leg) remain out.
Likely line-ups
Arsenal: Ramsdale; Tierney, Magalhães, Saliba, White; Xhaka, Partey; Martinelli, Ødegaard, Saka; Jesus
Nottingham Forest: Henderson; Williams, McKenna, Cook, Aurier; Kouyaté, Freuler, Yates; Lingard, Awoniyi, Gibbs-White
Key players
Taiwo Awoniyi (Nottingham Forest)
Has scored in both of Forest's wins, which were by 1-0 scorelines since the Reds returned to the top flight. Was the key man in all of his side's positive play against Liverpool and showed great instincts when he scored.
Granit Xhaka (Arsenal)
The Swiss has arguably been Arsenal's best player and his performance against Southampton, where he scored, was solid defensively, brilliant in possession and moved superbly, only reinforces that theory.
Match facts
Where is the match being played?
The Emirates Stadium is the host venue for this match.
What time is the match?
Kick-off is set for 3pm BST.
How can I watch the match?
There is no live coverage of this game, but Sky Sports will provide free highlights following the conclusion of the match.