Full-time: Liverpool fans will be delighted with Shaqiri's superb overhead kick and their side's second half performance. United fans won't be overly concerned, but will be even more relieved when players like De Gea, Matic, Pogba, Lingard and others finally return. Mourinho said before the tour started that he didn't care if his side lost by big margins, but while it's not a huge confidence blow, it's a missed opportunity for a confidence booster. That's what Liverpool have got, and Klopp will be pleased to finish his International Champions Cup campaign with an impressive victory.
89' The second half has been undeniably poor from United. The first half was encouraging against a stronger and fitter Liverpool side, but Mourinho's men have done nothing since the break while Liverpool have run riot against a team made up mainly of academy players.
86' The rest of the game will likely be played out at a pretty slow pace. Not much left to gain out of it. United fans will want it over and will be planning there "doesn't matter, it's a friendly" excuses and Liverpool fans will be overreacting and claiming it proves they'll be champions. Standard.
83' Official attendance is 101,254. Ridiculous. There are reasonable sized islands with smaller populations than that.
82' Goal! Bad result for United this, a great one for Liverpool, even if it's pre-season. Shaqiri becomes the second substitute to score, and it's a stunner. An overhead with perfect connection, unstoppable power and accuracy from eight yards out.
80' Substitutions for United as Josh Bohui, RoShaun Williams and Angel Gomes replace Ander Herrera, Axel Tuanzebe and Alexis Sanchez.
78' Jones running through on United's goal with Liverpool outnumbering their opponents 3 to 2 but Tahith Chong sprints back to take the ball off the 17-year-old and stop him from further extending Liverpool's advantage.
76' Sanchez has the chance to bring United back into the game but he's driven wide by Phillips, who does well by staying on his feet instead of diving in. He blocks Sanchez's shot and the Pereira corner is too deep.
75' That penalty decision is looking very odd. Seems like Robertson clipped his own foot and went down.
74' Goal! Liverpool extend their lead as Sheyi Ojo, the young Liverpool academy graduate, strikes past Joel Pereira in the United net. Confident strike from Ojo, who strolls up to the ball before powering it into the bottom left corner with his left boot.
73' Penalty! Another for Liverpool as Robertson is fouled by Ander Herrera in the box. The United captain is complaining.
72' Chong gets his first touch of the ball. He's ushered out of play, but his instinct is to go forward every time.
70' Substitutions for Man United: Fred and Tahith Chong come on for Mitchell and Mata. Debut for Brazilian Fred who signed for £52m from Shakthar Donetsk just before the World Cup began.
68' United haven't got going in this second half, and they haven't made a single change to their outfield selection. Expecting Fred to come on at some point, as well as Tahith Chong and Angel Gomes. That could be very shortly, and United need the boost.
65' Goal! Sturridge nets with his first touch after coming off the bench a minute ago. Bailly tries to muscle Shaqiri off the ball but he can't, and the Swiss international taps it back to Sturridge on the edge of the box who finishes well with his right foot.
63' Wholesale changes for Liverpool. Fabinho, van Dijk, Milner and Moreno off as well as Camacho and Sturridge. Looks like Robertson, Sturridge, Jones, Gomes, Chirivella and Grujic are on.
62' United free-kick from a good crossing position for Pereira or Mata. The Brazilian Pereira takes it but Sanchez can't get the powerful, whipped, low cross under control and his touch is gathered by the Liverpool goalkeeper Kelleher.
61' Intruder on the pitch. Commentators assure us he has "been dealt with". Sounds rather sinister. Maybe they deal with streakers with more ruthlessness in the USA...
60' More changes coming up for Liverpool. Andy Robertson will be on shortly, and perhaps a few more, including Joe Gomez. Fred is warming up for Man United.
58' Miscommunication between Joel Pereira and Tuanzebe but United manage to clear the ball away despite that.
53' This half is already shaping up to be less entertaining and competitive than the first. Slower pace to the game with both sides pressing with less effort.
48' Fabinho booked for a poor challenge on Alexis Sanchez. There have been quite a few late efforts to take the ball off Sanchez.
47' Fosu-Mensah shows brilliant pace to beat Solanke to a throughball. One of his many attributes. He and Tuanzebe in defence have impressed for United. The full-backs, Darmian and Mitchell, have been less good.
45' And we're underway for the second half after a feisty first period. Hopefully, we get something similar.
United, meanwhile, have replaced Lee Grant with Joel Pereira.
We'll be back underway shortly. Half-time subs for Liverpool see Shaqiri, Woodburn, Ojo, Kelleher and Phillips all on. Salah and Mane are off, we'll work out who else shortly.
Half-time: Some positives for both sides there. United's young stars look impressive, though Mitchell has struggled on the left as a wing-back. Fabinho for Liverpool in midfield has looked average at best, but last season's heroes of Mane and Salah have been lively. Camacho, meanwhile, has delivered some good crosses.
44' Axel Tuanzebe tracks Mo Salah well as the Egyptian threatens to cut back and deliver a typically fierce finish. The young United centre-back tackles well and nullifies the Salah threat. Grant saves easily from the resulting corner, but United left multiple Liverpool players unmarked and free.
42' Camacho delivers a powerful ball through the United box that required just a small flick of a stopped head to guide it in for a Liverpool lead, but no teammate can provide that.
37' Liverpool look threatening, but are hardly creating any fluent moves that build from defence to attack. Mainly scrappy chances for Klopp's side at the moment. For United, meanwhile, they've scored two offside goals and Pereira's struck a beautiful free-kick, but other than that they've created nothing.
35' The highlight of Pereira's pre-season will be that free-kick, but in reality, it's performances over 90 minutes which have made him stand out. His partnership with Sanchez has blossomed, and his confidence has grown. His defence-splitting passes through the lines are unique in United's midfield, and this should be his break-out season.
33' Demi Mitchell, who gave away the penalty, won that free-kick. He had a word with Mourinho during the drinks break, and after conceding the foul that let Liverpool take the lead, immediately asked for the ball, run down the pitch and won the free-kick. Will put any nerves at ease.
31' Goal! United hit back immediately. Stunningly good free-kick from Andreas Pereira. Struck with brilliant quality, right into the top left corner. Young Kamil Grabara doesn't even move.
30' Drinks break. Just before the half hour mark, the referee takes the post-goal moments as a chance for a drinks break in the heat.
28' Goal! Liverpool do lead, and it's Sadio Mane who took the spotkick at the Big House. Lee Grant gets close to stopping it, diving the right way, but Mane's finish is accurate and powerful.
27' Penalty! Liverpool have the chance to take the lead. Salah fouled by Demi Mitchell. Salah touches the ball before Mitchell's attempt at a clearance brings him down.
26' Fosu-Mensah tackles Sadio Mane, whose pace sees him latch onto the end of a long throughball in the penalty area.
25' Sanchez and Salah looking lively for their respective clubs. The latter is starting his first game of pre-season, so Liverpool fans will be pleased with that.
Chris Smalling update: I'm sure you are all waiting on tenterhooks for this. United say Bailly replaced the Englishman as a "precaution due to a minor injury". There you go, panic averted. You may now rest easy.
20' Mata scores for the second time this game, but he's offside again. Fantastic bit of play from Alexis Sanchez, who controls a powerful pass well and takes his marker out of the game with one touch before sending a pinpoint-accurate diagonal ball to the feet of Mata. The Spaniard controls beautifully, and finishes in the same fashion. But he was offside.
17' Pereira does well to win the ball in his own half, capitalising on a slip from Lallana. He carries possession forward and picks the right pass at the right time to Sanchez whose cross is blocked for a throw-in. Pereira has been a bright spark of the tour.
16' Alexis Sanchez is making some great runs as he hangs on the shoulder of the Liverpool defenders. Scott McTominay can't quite pick him up. I'm sure the Chilean will be pleased to have Paul Pogba back behind him in a couple of weeks.
14' Salah with another header on Lee Grant's goal. The United 'keeper saves easily this time.
12' United falling into an odd pattern of crisp passing at a good pace followed by a poor loss of possession, and repeat. Hardly going anywhere, but signs of the potential to do so.
10' The resulting corner sees Liverpool come very close once more, with a header guided across goal and somehow guided away out of the United penalty area.
9' Mo Salah in the thick of things early on. With his back to goal, the Egyptian flicks a cross on just with a nicely guided headed, but Lee Grant prevents it from dipping just under the crossbar with a fantastic save. Corner.
8' Mata finishes into the right corner, but the Spaniard had already been called offside after a long ball over the Liverpool defence. A good finish, nevertheless.
6' Ander Herrera with a late challenge on Sadio Mane. The 'never a friendly' cliché appears to be applicable to United, if not Liverpool, at this early stage.
5' Lee Grant with his first action of the game, coming off his line to gather a long throughball up to Mo Salah.
2' Two minutes in, and United's Pereira is already getting rough with James Milner, a little shove after a coming together. It is still United vs Liverpool
00:05 We're underway and You'll Never Walk Alone is still playing on the speakers. A few angry United fans...
00:04 Eric Bailly is apparently starting for Man United ahead of Smalling. A very late change there from Mourinho.
00:02 Teams in the tunnel. Man United wearing blue. Liverpool wearing white. Yeah, that's pre-season for you.
23:51 It looked like Bailly wasn't in United's squad, but the centre-back is now warming up on the pitch before kick-off. This is after the initial line-up tweeted out by the United account on social media had names appearing twice and additional players on the bench.
23:49 The Michigan Stadium is filling up with a crowd of around 100,000 expected. It's a huge experience for those playing today, including youngsters on either side.
23:15 Liverpool start with 19-year-old academy goalkeeper Kamil Grabara in goal, while it's a first start of the pre-season for Sadio Mane as well as Salah.
23:10 Fred could make his debut for United today. He's on the bench. But there's no Eric Bailly in the United matchday squad, so we must assume the Ivory Coast international has a small niggle.
23:06 United boss Mourinho as he stepped off the team coach, talking to Goal.com, "it's Liverpool first team vs Manchester United kids. For the last two years they have not been able to beat us, today they will think they have a chance."
21:01 Confirmation of that United team has come. Man United starting XI: Grant, Darmian, Fosu-Mensch, Smalling, Tuanzebe, Mitchell, McTominay, Herrera, Andreas Pereira, Mata, Alexis
20:56 Liverpool fans will be delighted to see Mo Salah in the starting line-up, as well as new signing Fabinho in midfield. Adam Lallana, meanwhile, is having a good pre-season after recovering from a serious injury which resulted in him not making England's World Cup squad.
20:54 Liverpool starting XI: Grabara, Camacho, Klavan, Van Dijk, Moreno, Fabinho, Lallana, Milner, Salah, Mane, Solanke
20:52 Tonight's Man United starting line-up will be out shortly, and Mourinho has elected to go with a 3-5-2 formation once more.
United, meanwhile, are playing at the Michigan Stadium for the second time. The last time was in 2014 as well, when a record crowd gathered to watch United beat Real Madrid 3-1 as Ashley Young netted twice and Javier Hernandez once. 109,318 fans watched on that occasion, a record for a football match in the USA. Saturday night's audience will likely be far lower. Ticket prices, the World Cup meaning weaker squads and the fact that United and Liverpool have visited the USA on multiple occasions during the last few years lead to this.
Of course, these two sides have faced off countless times back in England, but only one other time in the USA. That was in 2014 when a Louis van Gaal-led United beat Liverpool 3-1 to claim the International Champions Cup trophy. Wayne Rooney, Juan Mata and Jesse Lingard all scored for United, while it was Steven Gerrard who opened the lead for Liverpool.
Liverpool, meanwhile, have played just twice so far, with both games included in the International Champions Cup. They began with a 3-1 loss to German side, and Klopp's former club, Borussia Dortmund. Christian Pulisic scored twice in his home country to earn the plaudits. Liverpool then took on familiar foe Man City, and finished 2-1 winners against the Premier League champions in New Jersey.
After those first two initial fixtures, the Reds faced AC Milan in their opening game of the International Champions Cup. A 9-8 penalty shoot-out victory was bizarre in its length, but the 90 minutes prior to that laughable contest was better for United. Using a 3-5-2 formation, Mourinho tested with the idea of Sanchez up front alongside another striker, and the Chilean looked fantastic. His connection with Pereira, too, is building well and the pair were entertaining and effective, with Sanchez netting the opening goal.
United's pre-season has been mixed so far. Mourinho's side's first two games of their tour of the USA were both draws against reasonably easy opposition in Club America and San Jose Earthquakes. There were some positives, with the performances of Alexis Sanchez and Andreas Pereira impressing many. But much of the football was drab, and the main role of the games were for fitness building.
Both sides will be dotted with academy players here and there, but that is particularly true for United, who are missing many of their key men still, and their teams throughout the tour so far have been a mixture of youth players and fringe players.
Liverpool's hero of last season, Mo Salah, had a tough World Cup with Egypt, recovering from the shoulder injury he suffered in the Champions League final. He's back in action for Klopp's Reds, and came off the bench against Man City a few days ago.
Fred has now joined up with the Reds in the USA after a three-week break following his efforts in the World Cup with Brazil. He picked up an injury just before the tournament began, and so didn't play. He arrived in Los Angeles on Thursday and trained on Friday, but is unlikely to play against Liverpool.
United haven't been that quiet in the transfer window, though. Stoke City goalkeeper Lee Grant has been brought in to be the club's new third-choice shotstopper, allowing young Joel Pereira to leave on loan. Brazilian midfielder Fred was signed for £52m from Shakhtar Donetsk, and Mourinho has brought in Diogo Dalot, a 19-year-old who he deems the best young full-back in Europe.
In contrast, at Man United, not all fans are convinced by Jose Mourinho’s approach. That concern includes his style of play, his man management, his transfer record and his general aura off the pitch. The Portuguese boss has struck a glum figure over the last few weeks, and the spark in Mourinho that secretly endeared him to United fans during his days at Chelsea has seemingly disappeared.
However, for Liverpool, things are hugely positive. After reaching the Champions League final last year, only to be beaten by Real Madrid, lifting their third consecutive title, manager Jurgen Klopp has strengthened with major signings in goalkeeper Alisson, midfielders Fabinho and Naby Keita and forward Xherdan Shaqiri.
Two clubs who hate each other because they’re so similar. The Reds, meaning both of them of course, are the two most successful English clubs in history and have battled throughout the ages for dominance of the country’s biggest sport. Neither are currently the dominant force. That title lies with Manchester City.
Crowds for the International Champions Cup and other pre-season games in the USA have been limited. It’s a World Cup year, squads are missing many of the ‘stars’ of the teams touring the States, and most of these teams have been here before. But tonight it’s Manchester United vs Liverpool, and a big crowd will be expected, as always for this game.