The Boys In Blue have won three matches in a row, outscoring their oppponents 14-4, the second-most goals in a three-game span in MLS history.
Kansas City has lost seven consectuive matches on the road and are coming off of back-to-back draws against Columbus and Dallas.
Anton Tinnerholm continues his recovery from a torn Achilles and remains sidelined while Malte Amundsen is out with a lower body injury.
Star striker and reigning Golden Boot winner Valentin Castellanos is questionable with a lower body issue.
Gadi Kinda and Alan Pulido are out for the rest of the season after both underwent knee surgery.
Defenders Graham Zusi (thigh) and Nicolas Isimat-Marin (concussion) were forced to leave SKC's last two contests and will miss out here.
NYCFC: Johnson; Chanot, Morales, Callens, Gray; Acevedo, Parks; Magno, Rodríguez, Andrade; Castellanos
Sporting Kansas City: Meila; Ndenbe, Ford, Voloder, Zusi; Espinoza, Walter, Rosell; Sallói, Shelton, Russell
Ones to watch
Talles Magno (NYCFC)
The 19-year old, who clinched the Eastern Conference title last year with a late goal in Philadelphia, is second in the league with five assists and is proving to be a valuable player in attack, especially in the build-up play.
Remi Walter (Sporting Kansas City)
He's tied for the team lead in goals, but his league-leading total in distance covered (72.2 miles) and second in recoveries (94) will be vital in trying to contain the NYCFC attack from the midfield.
This is the first meeting between the two sides since 2019 when NYCFC came away with a 3-1 victory.
Tinnerholm opened the scoring four minutes from halftime and Heber doubled the Boys In Blue's advantage in the 54th minute.
Kansas City were reduced to ten men when Roger Espinoza was sent off in the 61st minute, but Ilie Sanchez halved the deficit in the 73rd minute.
Alexander Ring would restore the hosts' two-goal lead four minutes later for the final margin.
Kickoff is set for 7pm Eastern time.