A 3-1 victory over Minnesota snapped a three-match losing streak in MLS play for Seattle, who also lifted themselves off of the bottom of the Western Conference standings.
Defender Adam Lundqvist will miss out through suspension after picking up a red card in the win over Nashville.
Center back Teenage Hadebe is also missing as he picked up his fifth yellow card of the season last time out, triggering an automatic one-match ban.
Obed Vargas is out through yellow card accumulation, having been cautioned for the fifth time in the victory over Minnesota.
Houston Dynamo: Clark; Junqua, Hadebe, Parker, Zeca; Ceren; Dorsey, Rodriguez, Carrasquilla, Picault; Quintero
Seattle Sounders: Frei; Nouhou, Arreaga, Gómez, A. Roldán; Rusnák, Vargas; Morris, Lodeiro, C. Roldán; Ruidíaz
Ones to watch
Paulo Ferreira (Houston Dynamo)
Signed in the offseason from Paraguyan Primera Division side Club Libertad, the 24-year old has been solid so far, scoring four times and adding an assist in 772 minutes of action.
Cristian Roldan (Seattle Sounders)
He's been dominant all season long and put on one of his finest performances last time out against Minnesota, scoring a howitzer from deep, assisting on another and drew a penalty.
Last October, Houston ended an eight-match losing streak to Seattle with a 2-1 victory.
On 14 minutes, the Dynamo opened the scoring. Darwin Quintero sent in a free kick that was met by Maxi Urruti, who got behind the Seattle defense and finished Stefan Frei.
Just minutes later, just minutes later, Quintero made a nifty move to set himself up with a feed over Joao Paulo's head, then juked two more defenders before firing home.
Seattle pulled one back four minutes from halftime when Jimmy Medranda collected a deflected ball atop the 18-yard box and unleashed a shot that left a diving Michael Nelson no chance.
The match will be streamed nationally on ESPN+. In Houston, AT&T SportsNet will have all of the coverage while FOX 13+ has the action in Seattle.
Kickoff is set for 8:30pm Eastern time.