Nathan Jones' Luton Town make the trip to South Wales to face a Cardiff City side who are continuing in their struggles this season.
The Hatters go into Saturday's game after three consecutive 1-1 draws, but will certainly fancy their chances after a rather impressive start to the campaign.
The Bluebirds however, have struggled on home soil thus far, only picking up a single win in six games.
Tuesday night did not see any injuries for Neil Harris' side, but Cardiff could make a high number of changes in pivotal match against the Bedfordshire club.
Joe Ralls and Marlon Pack have not basked themselves in glory as of late, with Will Vaulks expected to be re-called to the starting line-up.
Josh Murphy returned to Cardiff's starting lineup on Wednesday night, but was not involved enough, to cement a starting place come Saturday. Harris may opt to use Robert Glatzel instead, for the additional aerial threat.
For Luton, it is a similar case of no fresh injuries, but the long-term absentees remain long off.
Kazenga LuaLua returned to training during the week and is likely to make the Hatters bench on Saturday.
George Moncur may return to the starting lineup on Saturday in the place of Elliot Lee, whilst James Bree could make his first start returning to the club in the summer.
Smithies; Bacuna, Morrison, Nelson, Bennett; Vaulks, Ralls, Harris; Wilson; Moore, Glatzel
Sluga; Bree, Pearson, Bradley, Norrington-Davies; Rea, Berry, Dewsbury-Hall; Cornick, Collins, Moncur
Ones to watch
From a Cardiff perspective, Liverpool loanee Harry Wilson is a player that they will want to keep getting the ball.
He possesses a wand of a left foot and has the ability to make these things happen in wide areas. Wilson has the ability to threaten from long-range and his ability to commit defenders is something that Luton will need to eliminate at source.
Kiernan Dewsbury-Hall is a player that is certainly thriving with confidence at the moment. He has received consecutive Man of the Match awards in the past two games and is a real danger man.
He is technically a very gifted player, who likes to pick the ball up in tight areas and turn his marker with trickery and his quick feet.
Cardiff were victorious on both occasions against The Town last year. Former Hatters forward Isaac Vassell secured the three points for The Bluebirds at the Cardiff City Stadium in stoppage time last season.
Cardiff completed the double over Luton in February thanks to a late Lee Tomlin goal, which left the Hatters bottom of the pile and eight points off safety.
Kick off time and how to watch
The game kicks off at 3:00 BST on Saturday and will be available to purchase via Cardiff's respective streaming platform or Luton's iFollow service.
Cardiff fans, click here:
Luton fans, click here:
After a relatively poor start to this campaign, Cardiff boss Neil Harris feels he is now playing for his job:
"If I answer that straight question with a straight answer, the realism is yes, that is football." He said.
"Let’s be realistic. You asked me the question (about playing for his job) because that’s what you think and that’s what most people think.
"I think this is a big period for me, the club and the group, the next couple of games. I put expectations on my own shoulders and I need players my to deliver and I need to get big calls right."
Luton Town manager Nathan Jones spoke about his opposite number on Saturday and was very complimentary towards Harris and his team.
“Neil Harris did a wonderful job last year, got them in the play-offs. The Championship is one of those things, someone told me once that you don’t have to do a hell of a lot different in the Championship to go four unbeaten or to get four or five defeats on the spin because it is that type of league." He said.
“Neil is experienced, they are not in a precarious position in anyway shape or form, far more teams in precarious positions, plus he brought himself a little bit of leeway because he has done fantastic work there.
“There's never a good time to play Cardiff, especially away, because they’re a tough side to play. They have got experienced Championship players, a lot with Premier League experience so it’s a tough, tough game."