Burnley head to Selhurst Park in search of a win that could see them go 11 points clear of the bottom three.
Sean Dyche’s men will be looking to bounce back from Tuesday night’s frustrating loss to Bournemouth in the FA Cup.
Meanwhile, Crystal Palace suffered a 2-0 defeat against Leeds in their last Premier League outing.
The Eagles enter the game six points ahead of Burnley, although the Clarets have a game in hand.
Palace star man Wilfried Zaha remains sidelined by a hamstring problem, while Joel Ward and James McArthur will be assessed before kick-off.
Burnley duo Nick Pope and Jack Cork are available after missing Tuesday’s FA Cup tie, while Charlie Taylor and Robbie Brady are “touch and go”.
Top scorer Chris Wood is still a doubt but Josh Brownhill is nearing a return to full fitness.
Crystal Palace: Guaita; Clyne, Dann, Cahill, Mitchell; Townsend, Milivojevic, Riedewald, Eze; Ayew, Mateta.
Burnley: Pope, Lowton, Tarkowski, Mee, Pieters; Gudmundsson, Westwood, Cork, McNeil; Barnes, Vydra.
- Dyche’s men have lost just one of seven matches against sides in the bottom eight this season, picking up 12 points
- A win would see Palace reach 29 points – their highest tally at this stage of the season since 1991-92
- Only Aston Villa have kept more than Burnley’s five away clean sheets in the Premier League this season
The Clarets recorded a narrow 1-0 win when the sides met at Turf Moor in the reverse fixture back in November.
Chris Wood got the only goal with a ruthless finish after pouncing on Jay Rodriguez’s knock-down.
Palace nearly drew level in injury time but Nick Pope made a heroic stop from close range to deny Christian Benteke.
It was Burnley’s first league win of the campaign and saw Dyche’s men climb out of the bottom three.
How to watch
Saturday’s game is live on Sky Sports for UK viewers (KO 3pm).