The Chairboys come into the game off the back of a humiliating 7-2 defeat away at Brentford on Saturday. Wycombe managed to go into the half-time break level at 2-2 before capitulating in the second half. The home side are 11 points off safety and are yet to record a point in 2021 so Gareth Ainsworth will be desperate to pick up all three points on Tuesday.
Birmingham are also a side struggling to find form at the minute with just one win in nine league games. They come into the game following a 1-1 home draw against Coventry City in which Jeremie Bela's emphatic 18th-minute penalty was cancelled out by Gustavo Hamer's powerful strike just 11 minutes later. The Blues are just two points above 22nd-placed Rotherham United who have two games in hand on Aitor Karanka's side.
After an awful second-half performance at Brentford on Saturday, Ainsworth is likely to make some changes to the Wycombe starting lineup. Jordan Obita could make his debut at left-back after signing from Oxford United. This would see Jason McCarthy move into midfield. Wycombe currently have some issues in defence as Anthony Stewart, Joe Jacobsen and Ryan Tafazioli are all out injured.
Aitor Karanka could hand Rekeem Harper his full league debut in midfield following his loan move from West Bromwich Albion. It is still to be seen whether Karanka will stick with Scott Hogan at centre-forward or if he will bring in Lukas Jutkiewicz. Birmingham do not currently have any first-team injury problems.
Allsop; Grimmer, Charles, Knight, Obita; McCarthy, Adeniran, Bloomfield, McCleary; Muskwe, Ikpeazu.
Etheridge, Colin, Dean, Jose, Friend; Harper, Sunjic; Sanchez, Toral Bela; Jutkiewicz.
Ones to watch
Wycombe signed the 22-year-old striker from Leicester City at the start of the January transfer window and he made his league debut on Saturday away at Brentford. He bagged a debut goal with a 43rd-minute header to make the score 2-2. Muskwe has made a promising start for The Chairboys and they will be hoping he can help steer them away from relegation.
The 28-year-old has impressed on the right-wing for Birmingham this season, with two man of the match awards from his 22 starts. The Spaniard has only scored once this season but if he is able to improve his numbers he could be a real asset to Birmingham in their battle to stay in the Championship. Sanchez is very adept at taking set-pieces and is also a very good crosser of the ball, which is very useful when combined with proven target man Jutkiewicz at centre forward.
When the two sides met at St. Andrews Trillion Trophy Stadium back in early November, Wycombe came back from behind to win 2-1 thanks to a 91st-minute own goal from Birmingham defender Kristian Pedersen.
How to Watch
Kick-off is at 19:00 BST on Tuesday 2nd February and the match is available to watch on both clubs' iFollow streaming service for a fee of £10.