Nicolas Pepe shone as the Gunners moved into the top half of the Premier League table coming from behind to secure the three points at the King Power.
Leicester were yet again hit by more injuries as Harvey Barnes and Jonny Evans both couldn't continue with Barnes' looking the worst out of the two.
More injury problems
At this rate, Leicester fans are unsure when this ongoing injury problem will ever end.
The latest to join the ever growing injury list is Harvey Barnes. The inform winger was stretchered off as a precaution, however it's now feared the 23-year-old could be out for up to six weeks.
It is set to be a huge blow for the Foxes. Barnes has 17 goal contributions this season and has been one of their most instrumental players thus far.
Jonny Evans also had to go off with a suspected calf injury. The Northern Ireland international has been playing with a dead calf for a weeks now, and has had plenty of knocks this season.
Being such an instrumental character in Brendan Rodgers' side this season, if he is missing for an extended period, he will also be a loss.
Nicolas Pepe shines
Nicolas Pepe was at the focal point of the Gunners' attack and caused many problems to Leicester's fullbacks throughout the game.
Luke Thomas struggled massively in the first half, leading him to be hooked for Marc Albrighton at half time.
Pepe scored the third goal, and crossed the ball which led to the penalty that Alexandre Lacazette calmly converted.
He played a key part in the win for the North Londoners, rising to previous criticism he has received this season.
Arsenal's season back on track?
After an expected season of ups and downs so far, Arteta's men would have had a real confidence boost after their first win in their last four attempts against the Foxes.
Building on their dramatic Europa League win in midweek, Arsenal fans have plenty to look forward to in the remainder of the season, with a round of 16 clash against Olympiakos coming up as well as the Premier League run in.
However, it's not going to be easy. They face the Greek champions twice in March, alongside Spurs and Liverpool in the League in what could prove to be a pivotal month in the Gunners' season.