The Magpies come into this clash coming off the back of a 3-1 victory over fellow strugglers Everton on Tuesday night.
Here VAVEL looks at the potential changes that could be made to Newcastle's starting line-up tomorrow.
Forced switches at both full-back positions?
Loanee Matt Targett is unable to field for Howe this time round as he is facing his parent club, this means that there is a vacant left back spot for a potential debutant.
This debutant being the Blyth-born Dan Burn whose flexibility across the back line could come in handy for the Magpies on Sunday.
He has repeatedly been operated as a left back and left wing back for his former side Brighton & Hove Albion where he was more than capable and put in solid performances.
However there is the familiar face of Javier Manquillo who has been pushed out of the team due to the signing of Kieran Trippier but made an admirable cameo performance in Newcastle's away win at Elland Road against Leeds United where he featured at left back. Here he dealt with the dangerous Raphinha who has been known to terrorise defences this season.
But Manquillo's services may be required elsewhere across the back four after it was reported today by Eddie Howe in his press conference that Trippier faces a late fitness test after hobbling off with a suspected calf injury against Everton.
Howe will be hopeful that Trippier can make an appearance after an outstanding performance defensively topped off with a wonderful free kick to warp up the three points for the Toon.
So with his potential admission from the match day squad we could see Manquillo fill in there with Burn at left back. However there are the options of Jacob Murphy and Emil Krafth who have both played in that role this season, so Howe definitely has choices to choose from and will have to assess them well.
Bruno to start?
There isn't just the defensive headache for Howe though as he has the option to hand another player a full debut at St James' Park, Newcastle's fourth January signing, Bruno Guimaraes.
He did feature midweek but for only six minutes, but even with those limited minutes on the pitch he excited the Geordie faithful with a superb back heel pass, alongside a near assist to Allan Saint-Maximin, giving the fans the impression theres more to come from the £35 million man.
The only issue is, Howe will not want to disturb the team chemistry too much after a convincing victory, but will surely know Guimaraes' quality could well win him his third game in a row.
If he was to come into the team it would have to be from one of three, the three being Joelinton, Jonjo Shelvey and Joe Willock, and with them all performing well last time out, it is going to be a difficult decision to make.
So it is clear that Howe has decisions to make defensively and midfield wise, but we'll have to wait in anticipation for Sunday at 1pm to see what he ended up choosing as his starting line-up.