Maurizio Sarri's side dismantled Dynamo Kiev 5-0 in the second leg of their round of 16 tie, ending with an 8-0 aggregate score across both fixtures.
Olivier Giroud grabbed a hat-trick, whilst Marcos Alonso and teenager Callum Hudson-Odoi also got in on the act during Chelsea's crushing in Kiev.
Despite not making it onto the score sheet, Loftus-Cheek conquered the midfield with his strength and athleticism, which Dynamo could simply not detain.
"He did very well. He is improving in the last month. He has been able to train after the problem with the back", spoke Sarri to BT Sport, upon Loftus-Cheek's eighth appearance in the competition this campaign. "He had a wonderful match and I'm really happy he could play for 90 minutes."
"His potential as a player is very, very high. Physically, technically and tactically he is improving, he can become one of the best midfielders not only in England but in Europe."
Loftus-Cheek call up
Shortly after being named in Gareth Southgate's 23 man England squad for the upcoming European Championship qualifiers, Loftus-Cheek put in a performance that should have the Lions boss beaming with joy.
However, he is still not guaranteed a starting spot in the Premier League, with Sarri favouring a midfielder trio of Jorginho, N'Golo Kante and either Mateo Kovacic or Ross Barkley.
Chelsea fans, on the other hand, will be calling for Loftus-Cheek to start against Everton on Sunday after demonstrating he can take a match by the scruff of its neck, a trait lacking in this current Chelsea crop.
Sarri also spoke to BT Sport about another of his young English enigmas. "I think he played very well, better in the second half," he said when asked about Hudson-Odoi's display.
"We found a lot of spaces and Callum in the spaces is a very good player. I am very happy for him, he has to keep the feet on the ground because he is very young and can improve more."
Like Loftus-Cheek, Hudson-Odoi capped a call up to the Aidy Boothroyd's U21s squad with a goal against Dynamo, his fourth in Europe this season.
He is another that Blues supporters will be desperate to get game time in the Premier League, especially if Bayern Munich come searching for his signature again in the summer.