Mason Mount won a penalty for his side in the 53rd minute, converting it to level the game and cancelling out Takumi Minamino's smartly finished opener.
Chelsea once again looked creative and promising for most of the game but were unable to dismantle Ralph Hasenhuttl's Saints in the final third, even after having 71% possession.
Summer signing Hakim Ziyech came on with 15 minutes to go, however he made a familiar looking cameo as he was unable to make an impact on the game.
It was suggested that the home side were playing for a draw. Hasenhuttl confirmed this when speaking to the press after the game "A draw is like a win for us today."
Thomas Tuchel admitted after the game that he wasn't happy with Callum Hudson-Odoi's "application and attitude" after he brought the youngster off for Ziyech after he had already brought him on for Tammy Abraham at half time.
Sacrifice in preparation for Atletico
Thomas Tuchel made a couple of changes to his starting eleven for the game, Leaving out Ben Chilwell, Callum Hudson-Odoi and Jorginho out of the line up. This alludes to the notion that Tuchel decided to rest some of his most trusted players for Tuesday's fixture against Atletico Madrid in the Champions League
The Blues had a few opportunities in the first 20 minutes to kill the game off early but lacked the aggression and desire in and around the penalty area to hurt their opponents. Southampton sat back for the rest of the game and soaked up pressure to see out the draw.
Tuchel will have to rally his team and bolster their ability to create attacking scenarios before they travel to Madrid next week, as the Spanish side are regarded for their defensive prowess in any game, whatever the importance.
Mason Mount shines again
Mount was once again the shining light in the Chelsea side, winning his team a penalty and scoring the equaliser that allowed his manager to keep his unbeaten streak since becoming Blues boss.
Naturally being played in the "hole" just in front of his other two central midfield partners, the England international is constantly creating opportunities, getting in behind and shooting from range which showcases his versatility as an attacking player.
Although unable to help his side get the win, in a game that felt like two points lost he stood out as Chelsea's player of the match. Pundit Joe Cole declared after the match that the 22 year old has it in him to be future captain of the West-London outfit. No doubt he'll be starting on Tuesday night...